DIRENE Paste, 15 ml

Formula for dogs and cats: Support in drug or food therapies in cases of acute renal failure (IRA). 

Direne Paste 15 ml contains: Astragalus membranaceum (Astragalus) 12,500; Betula pendula (Birch) 12,500; Vaccinium macrocarpum (Merisor) 7,500; Curcuma longa (Turmeric) 1,500; Sophora Japonica (Quercetin) 6,250; 3rd Vitamins and Provitamins Vit. E (all-rac-α-tocopheryl-acetate) 10,000 ;1a Preservatives E332 Potassium Citrate 50,000 ;2k Microorganisms Enterococcus faecium - 2x1010 cfu / g 7,400.

Recommended dosage: 1 graduated syringe/5 kg gc., once a day, for at least 4 months.

Direne - allows time for urea to decrease in the digestive tract, preventing gastric and duodenal ulcers, and through the specific treatment for IRA, kidney functions can be restarted. It also has a powerful analgesic and anti-inflammatory effect at the level of the nephron. 

Properties of DIRENE active substances: Ganoderma Lucidum - mushroom with cortisone activity - reduces inflammation at the renal level!!! 

Proven antioxidant effect! Similar effect to that of cortisone - it acts more slowly, but just as precisely and without side effects. 

• Anti-inflammatory effects similar to Diclofenac (Soniamol, 2009)

• Antiallergic action – antihistaminic – contains tritrepenoids

• Eliminates the production of allergic antibodies – prevents the occurrence of allergic reactions. 

• Protects the renal endothelium against cell degeneration in the case of proteinuria.

Astragallus - Herbaceous plant - traditional Chinese medicine - immunostimulating properties, excretion of sodium, reducing proteinuria. 

Effective in nephritis that do not respond to diuretics. 

Turmeric- Contains curcumin which inhibits Cox2 enzymes and implicitly prostaglandin formation => anti-inflammatory action.
Chitosan - polymer of D-Glucosamine, also obtained by alkaline deacetylation of chitin.

Binds Phosphorus Cranberry Extract - beneficial action on the lower urinary tract - prevents the adhesion of G- bacteria (E.coli, Proteus, Klebsiella, Enterobacter, Pseudomonas) to mucous membranes of the urinary tract, ↓the amount of uric acid that could lead to the formation of urate crystals. 

Quercitin - bioflavonoid - anti-inflammatory, antioxidant, protects against free radicals that lead to oxidative stress - common in kidney diseases.

 Yucca Schidigera - Reduces nitrogen in the intestine and improves protein digestion. 

Birch- Very effective as a depurative due to the high content of potassium salt. 

The ratio ↑K/Na stimulates the elimination of urine, without irritating the renal parenchyma, while Vit.