VetPlus Epilease 1000 mg 60 capsules – nutraceutical supplement used for long-term treatment of epilepsy.
In recent years the use of potassium bromide for the treatment of Epilepsy, has won the approval of veterinarians. It is particularly beneficial for dogs that have a poor response to phenobarbitone, dogs with liver disease, liver toxicity as a result of the use of phenobarbitonics.
Composition: Magnesium stearate, Microcrystalline cellulose.
Additives: Potassium bromide 1000 mg/kg.
Indications
The capsule can be taken as such or opened, mixing its contents with food. Do not administer on an empty stomach.
To be administered with regular meals
Loading dose administration protocol
A total dose of 120mg/kg/day+ maintenance dose is administered, administered in four halves per day.
The stable blood dose will be reached after 5 days of administration.
Continue with the maintenance dose starting with day 6.
Side effects such as behavioural changes and/or ataxia may be observed.
Medical supervision is recommended during the administration of the loading dose - for the occurrence of overdose and the appearance of toxicity.
Maintenance dose:
Administered with phenobarbital 25 -40mg/kg/day
Administered as a single therapeutic agent 50 -80mg/kg/day
Stable serum levels are obtained after 4 months of administration.
After a month of administration the percentage of stability is 60% which allows dose adjustment. The gradual reduction of phenobarbital can be done two months after continuous therapy with Epilease. Usually, a single daily admninistration is recommended.
If Gastrointestinal disorders occur (e.g. vomiting) the dose will be administered in two halves.