Indications:
Kreon is indicated in the treatment of exocrine insufficiency, caused by:
- cystic fibrosis of the pancreas;
- chronic pancreatitis;
- pancreatectomy;
- total gastrectomy;
- partial gastric resection (Billroth I/II);
- neoplastic ductal obstruction (e.g. in neoplasm of the pancreas or common bile ducts).
Pancreatic enzyme supplementation may also be useful in the treatment of pancreatic pain or late allograft pancreatitis and exocrine pancreatic insufficiency in the elderly.
Method of administration:
The dosage is adapted to individual needs and depends on the severity of the disease and the content of the food.
In adults (including the elderly) and children: initially one or two capsules with each main meal and one capsule with each snack, then adjust the dose according to response.
Clinical experience shows that the effective dose can be between 5 and 15 capsules daily. The capsules should be swallowed with sufficient liquid (approximately 100 ml).
It is recommended to take half or a third of the total dose at the beginning of the meal and the rest during the meal. Capsules and microspheres should be swallowed whole, without chewing or swallowing.
If swallowing the capsules is difficult (eg in children or elderly patients), the capsules can be opened and the minimicrospheres added to a light meal that does not require chewing or taken with liquid. Any mixture of minimicrospheres in food or liquid should be taken immediately and should not be stored.
Chewing or crushing the minimicrospheres, as well as adding the minimicrospheres to food with a pH greater than 5.5 destroys the protective enteric coating.
Presentation:
20 gastro-resistant capsules